Prelude to pancuronium and vecuronium
نویسندگان
چکیده
منابع مشابه
Comparison between the continuous infusion of vecuronium and the intermittent administration of pancuronium and vecuronium.
The neuromuscular blocking effects of repeated bolus injections of pancuronium, or vecuronium, and of the continuous infusion of vecuronium have been compared in 36 patients by means of evoked twitch tension. Groups I and II received a loading dose (0.075 mg kg-1) of pancuronium or vecuronium, respectively, followed by 0.015-mg kg-1 maintenance doses when twitch tension had recovered to 25% of ...
متن کاملPotentiation of pancuronium and vecuronium neuromuscular blockade by intravenous salbutamol.
Three doses of salbutamol 125 micrograms iv were given, over 3.5 hr, to a 28-yr-old healthy, previously non-asthmatic man during thiopentone-O2/N2O-isoflurane anaesthesia for treatment and prophylaxis of bronchospasm. Force of contraction of the adductor pollicis was measured before and after the last two injections. Initially, the patient was given pancuronium, 5 mg. Salbutamol, 125 micrograms...
متن کاملAtracurium, vecuronium and pancuronium in end-stage renal failure. Dose-response properties and interactions with azathioprine.
Dose-response relations for atracurium, vecuronium and pancuronium were determined in patients in end-stage renal failure for the initial neuromuscular blockade (using three cumulative doses) and for the maintenance of stable 90% response (during continuous infusion). All measurements were during renal transplant surgery, and the interaction of azathioprine on neuromuscular blockade was estimat...
متن کاملSimultaneous determination of pancuronium, vecuronium and their related compounds using LC-ESI-MS.
A simultaneous determination method of quaternary amino steroidal muscle relaxants, pancuronium (PAN), vecuronium (VEC), and 17-monodesacetyl pancuronium (17-OH-PAN), 3,17-bisdesacetyl pancuronium (3,17-OH-PAN), 3-monodesacetyl vecuronium (3-OH-VEC), 3,17-bisdesacetyl vecuronium (3,17-OH-VEC) in human serum was developed using liquid chromatography-electrospray ionization-mass spectrometry (LC-...
متن کاملInteractions of diisopropyl phenol (ICI 35868) with suxamethonium, vecuronium and pancuronium in vitro.
In vitro studies were performed using the rat phrenic nerve-hemidiaphragm preparation to investigate possible interactions between diisopropyl phenol and its solvent, cremophor, with three neuromuscular blocking drugs. Cumulative concentration curves were constructed for the neuromuscular blockers and linear regression analyses performed. Differences in the calculated effective concentration to...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 2000
ISSN: 0003-2409
DOI: 10.1046/j.1365-2044.2000.01423.x